He had increased FSH, low LH, normal testosterone, normal SHBG (20.6 nmol/l) and hyperprolactinaemia. Pituitary macroadenoma with chiasmal compression was found. Haemoglobin normalised post-operatively.Ĭase 2: 39-year-old man with a few months history of headaches and bitemporal hemianopia. Pituitary surgery was performed pathology: adenoma with focal positivity for FSH and diffuse positivity for LH. He did not report manifestations related with high testosterone but he had polycythaemia. He had increased gonadotropins, increased testosterone, normal SHBG, hyperprolactinaemia, ACTH/ TSH deficiency. Imaging showed macroadenoma compressing optic chiasm. Herein, we present three males with elevated, normal or low testosterone at diagnosis.Ĭases: Case 1:42-year-old man with two-year history of visual impairment. In males, typically, FSH levels are elevated, whereas LH and testosterone are variable. Introduction: Functioning gonadotroph adenomas (FGAs) are very rare tumours secreting biologically active gonadotropins.
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